Neurodegenerative diseases

Neurodegenerative diseases are usually slowly progressive, hereditary or sporadically occurring disorders of the nervous system. The main feature is the progressive loss of nerve cells. It can damage the central (brain and spinal cord) as well as on the peripheral nervous system.

This leads to various neurological diseases of the brain such as:

  • Dementia (e.g., Alzheimer's disease)
  • Movement disorders (e.g., Parkinson's disease or chorea)
  • Multisystem atrophies (combination of demential development, vegetative abnormalities and complex movement disorders)

In cases when the spinal cord or the peripheral nerves are affected:

  • Paralysis and muscular degeneration (e.g., spinal muscular atrophy)
  • Gait disorders (spastic paraplegia)
  • Hypersensitivity and paralysis, mainly of the lower extremities (HSMN = congenital nerve degeneration, the so-called Hereditary Sensory and Motor Neuropathy)